انجام تست خراش پوستی با آلرژن های شایع غذایی درکودکانی با پروکتوکولیت ناشی از پروتئین

Mozhgan Moghtaderi © ℗, Sara Mostafavi , Naser Honar , Khadijehsadat Najib

انجام تست خراش پوستی با آلرژن های شایع غذایی درکودکانی با پروکتوکولیت ناشی از پروتئین

کد: G-1035

نویسندگان: Mozhgan Moghtaderi © ℗, Sara Mostafavi , Naser Honar , Khadijehsadat Najib

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خلاصه مقاله

Background: Food protein-induced allergic proctocolitis (FPIAP) is a non-IgE-associated disease with some evidence of IgE sensitization in a minority of patients.This study aimed to determine the prevalence of IgE sensitization to common foods by skin test and find its correlation for milk outgrowing in infants with FPIAP during a follow-up of 5 years. Methods: This prospective cross-sectional study included infants with FPIAP in 2016. Skin prick tests were done with commercial extracts of 11 common food allergens. We followed these infants for five years, and the resolution was established by successfully ingesting cow’s milk. Results: Of 126 infants analyzed, 81 infants (40 boys and 41girls) with FPIPC completed this study. The frequency of food sensitization was 32% to at least one of the applied food allergens. Cow's milk (13.6%), egg (13.6%), and beef (6.2%) were the most frequent allergens, respectively. In this study, 45.7% of the infants developed a tolerance to the milk by the age of one year, 77.1% by the age of two, 91.3% by the age of three, and 96.3% by the age of four. Positive food sensitization and prematurity were significantly correlated with the likelihood of developing a cow's milk tolerance (P 0.001). Conclusion: This study suggests pointing out skin tests of infants with FPIAP for common food allergens because IgE- mediated sensitization can infer a greater chance of a persistent course of milk tolerance.

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